The 12 Brain Rules
Louise Page • February 18, 2026

12 Principles for Thriving and Surviving at Work, Home, and School

Are John Medina's 12 Brain Rules Still Scientifically Accurate?


Yes. A 2023 peer‑reviewed review concludes that newer research continues to validate Medina’s original 12 rules and supports their relevance across modern learning and cognitive science settings. [ijefm.com]


Medina’s rules are also grounded in peer‑reviewed, replicated research, which he specifically cites throughout his book, Brain Rules

What Are the 12 Brain Rules?

1. Exercise – Exercise boosts brain power

Aerobic activity improves cognition, memory, and executive control.
Video: Exercise boosts brain power (Vimeo)


2. Survival – The human brain evolved, too

Human intelligence is shaped by evolutionary pressures favoring adaptability.
Video: Survival (Vimeo)


3. Wiring – Every brain is wired differently

No two brains are alike; experiences rewire the brain (neuroplasticity).
Video: Wiring (Vimeo)


4. Attention – We don’t pay attention to boring things

Emotion, novelty, and meaning drive attention.
Video: Attention (Vimeo)


5. Short‑Term Memory – Repeat to remember

Working memory is limited; repetition strengthens encoding.
Video: Short‑term memory (Vimeo)


6. Long‑Term Memory – Remember to repeat

Repeated retrieval helps consolidate memory long‑term.
Video: Long‑term memory (How memory works – Vimeo)


7. Sleep – Sleep well, think well

Sleep enhances attention, memory, and problem‑solving.
Video: Sleep (Vimeo)


8. Stress – Stressed brains don’t learn the same way

Chronic stress impairs memory and learning.
Video: Stress (Vimeo)


9. Sensory Integration – Stimulate more senses

Multisensory experiences enhance learning.
Video: Sensory Integration (Vimeo)


10. Vision – Vision trumps all other senses

Visual input is processed faster and retained better than other sensory information.
Videos:


11. Gender – Male and female brains are different

Sex‑based differences exist in emotional processing, stress responses, and certain cognition patterns.
Video: Gender differences (Vimeo)


12. Exploration – We are powerful and natural explorers

Curiosity drives learning; the brain thrives on exploration and novelty.
Video: Exploration (Vimeo)





🎥 Additional Full Presentations

Full “Brain Rules” Talk (Talks at Google)

“12 Brain Rules” Summary Video